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6GRZ

Crystal structure of the light chain dimer mH6

Summary for 6GRZ
Entry DOI10.2210/pdb6grz/pdb
Related5MUD
DescriptormH6, GLYCEROL (3 entities in total)
Functional Keywordslight chain dimer, light chain amyloidosis, immunoglobulin fold, protein aggregation, immune system
Biological sourceHomo sapiens
Total number of polymer chains2
Total formula weight46129.07
Authors
Maritan, M.,Ricagno, S.,Ambrosetti, A.,Oberti, L. (deposition date: 2018-06-13, release date: 2019-06-12, Last modification date: 2024-01-17)
Primary citationMaritan, M.,Romeo, M.,Oberti, L.,Sormanni, P.,Tasaki, M.,Russo, R.,Ambrosetti, A.,Motta, P.,Rognoni, P.,Mazzini, G.,Barbiroli, A.,Palladini, G.,Vendruscolo, M.,Diomede, L.,Bolognesi, M.,Merlini, G.,Lavatelli, F.,Ricagno, S.
Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains
J.Mol.Biol., 2020
Cited by
DOI: 10.1016/j.jmb.2019.12.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

217705

건을2024-03-27부터공개중

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