6GR9
Human AURKC INCENP complex bound to VX-680
Summary for 6GR9
Entry DOI | 10.2210/pdb6gr9/pdb |
Descriptor | Aurora kinase C, Inner centromere protein, CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, ... (5 entities in total) |
Functional Keywords | kinase, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 41030.15 |
Authors | Abdul Azeez, K.R.,Sorrell, F.J.,von Delft, F.,Bountra, C.,Knapp, S.,Edwards, A.M.,Arrowsmith, C.,Elkins, J.M. (deposition date: 2018-06-10, release date: 2019-05-15, Last modification date: 2024-01-17) |
Primary citation | Abdul Azeez, K.R.,Elkins, J.M. AURKC INCENP complex bound to BRD-7880 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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