6GQY

KRAS-169 Q61H GPPNHP + CH-3

Summary for 6GQY

Entry DOI	10.2210/pdb6gqy/pdb
Related	6GOD 6GOE 6GOF 6GOG 6GOM
Descriptor	GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (5 entities in total)
Functional Keywords	kras, oncoprotein
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	121918.94
Authors	Cruz-Migoni, A.,Quevedo, C.E.,Carr, S.B.,Phillips, S.V.E.,Rabbitts, T.H. (deposition date: 2018-06-08, release date: 2019-02-06, Last modification date: 2024-01-17)
Primary citation	Cruz-Migoni, A.,Canning, P.,Quevedo, C.E.,Bataille, C.J.R.,Bery, N.,Miller, A.,Russell, A.J.,Phillips, S.E.V.,Carr, S.B.,Rabbitts, T.H. Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds. Proc. Natl. Acad. Sci. U.S.A., 116:2545-2550, 2019 Cited by PubMed: 30683716 DOI: 10.1073/pnas.1811360116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation