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6GNM

Crystal Structure Of Sea Bream Transthyretin in complex with 2,2',4,4'-tetrahydroxybenzophenone (BP2)

Summary for 6GNM
Entry DOI10.2210/pdb6gnm/pdb
DescriptorTransthyretin, bis(2,4-dihydroxyphenyl)methanone (3 entities in total)
Functional Keywordstransport protein, thyroxine disrupting chemicals, tdcs, 2, 2', 4, 4'-tetrahydroxybenzophenone, bp2
Biological sourceSparus aurata (Gilthead sea bream)
Total number of polymer chains4
Total formula weight58312.81
Authors
Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (deposition date: 2018-05-31, release date: 2018-07-11, Last modification date: 2024-01-17)
Primary citationZhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E.
Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.
Environ. Sci. Technol., 52:11865-11874, 2018
Cited by
PubMed: 30226982
DOI: 10.1021/acs.est.8b03581
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.24 Å)
Structure validation

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