6GL7
Neurturin-GFRa2-RET extracellular complex
Summary for 6GL7
Entry DOI | 10.2210/pdb6gl7/pdb |
EMDB information | 0026 |
Descriptor | Neurturin, GDNF family receptor alpha-2, Proto-oncogene tyrosine-protein kinase receptor Ret (3 entities in total) |
Functional Keywords | neurotrophic signalling, receptor tyrosine kinase, gdnf family of ligands, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 255986.77 |
Authors | Bigalke, J.M.,Aibara, S.,Sandmark, J.,Amunts, A. (deposition date: 2018-05-23, release date: 2019-08-14, Last modification date: 2019-12-18) |
Primary citation | Bigalke, J.M.,Aibara, S.,Roth, R.,Dahl, G.,Gordon, E.,Dorbeus, S.,Amunts, A.,Sandmark, J. Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain. Sci Adv, 5:eaau4202-eaau4202, 2019 Cited by PubMed: 31392261DOI: 10.1126/sciadv.aau4202 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.3 Å) |
Structure validation
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