6GL7

Neurturin-GFRa2-RET extracellular complex

6GL7 の概要

• エントリーDOI: 10.2210/pdb6gl7/pdb
• EMDBエントリー: 0026
• 分子名称: Neurturin, GDNF family receptor alpha-2, Proto-oncogene tyrosine-protein kinase receptor Ret (3 entities in total)
• 機能のキーワード: neurotrophic signalling, receptor tyrosine kinase, gdnf family of ligands, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 255986.77

構造登録者

Bigalke, J.M.,Aibara, S.,Sandmark, J.,Amunts, A. (登録日: 2018-05-23, 公開日: 2019-08-14, 最終更新日: 2019-12-18)

• 主引用文献: Bigalke, J.M.,Aibara, S.,Roth, R.,Dahl, G.,Gordon, E.,Dorbeus, S.,Amunts, A.,Sandmark, J.; Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain.; Sci Adv, 5:eaau4202-eaau4202, 2019; PubMed: 31392261; DOI: 10.1126/sciadv.aau4202

実験手法

ELECTRON MICROSCOPY (6.3 Å)