6GJV
apo-structure of IMPDH from Pseudomonas aeruginosa
Summary for 6GJV
| Entry DOI | 10.2210/pdb6gjv/pdb |
| Descriptor | Inosine-5'-monophosphate dehydrogenase (2 entities in total) |
| Functional Keywords | inosine-5'-monophosphate dehydrogenase, oxidoreductase |
| Biological source | Pseudomonas aeruginosa PAO1 |
| Total number of polymer chains | 8 |
| Total formula weight | 431509.59 |
| Authors | Labesse, G.,Haouz, A.,Alexandre, T.,Munier-Lehmann, H. (deposition date: 2018-05-17, release date: 2019-02-27, Last modification date: 2024-01-17) |
| Primary citation | Alexandre, T.,Lupan, A.,Helynck, O.,Vichier-Guerre, S.,Dugue, L.,Gelin, M.,Haouz, A.,Labesse, G.,Munier-Lehmann, H. First-in-class allosteric inhibitors of bacterial IMPDHs. Eur J Med Chem, 167:124-132, 2019 Cited by PubMed: 30769241DOI: 10.1016/j.ejmech.2019.01.064 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.11 Å) |
Structure validation
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