6GJH

Human Hsp27 (HspB1) alpha-crystallin domain in complex with a peptide mimic of its phosphorylatable N-terminal region

Summary for 6GJH

• Entry DOI: 10.2210/pdb6gjh/pdb
• Descriptor: Heat shock protein beta-1, ALA-LEU-SER-ARG-GLN, LEU-SER-GLY-VAL, ... (6 entities in total)
• Functional Keywords: ig-fold, shsp, chaperone
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 79676.54

Authors

Collier, M.P.,Benesch, J.L.P. (deposition date: 2018-05-16, release date: 2019-05-29, Last modification date: 2024-01-17)

• Primary citation: Collier, M.P.,Alderson, T.R.,de Villiers, C.P.,Nicholls, D.,Gastall, H.Y.,Allison, T.M.,Degiacomi, M.T.,Jiang, H.,Mlynek, G.,Furst, D.O.,van der Ven, P.F.M.,Djinovic-Carugo, K.,Baldwin, A.J.,Watkins, H.,Gehmlich, K.,Benesch, J.L.P.; HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C.; Sci Adv, 5:eaav8421-eaav8421, 2019; PubMed: 31131323; DOI: 10.1126/sciadv.aav8421

Experimental method