6GI5

Crystal structure of the ferric enterobactin esterase (PfeE) from Pseudomonas aeruginosa in complex with the tris-catechol vector

Summary for 6GI5

• Entry DOI: 10.2210/pdb6gi5/pdb
• Descriptor: Ferric enterobactin esterase, FE (III) ION, ~{N}-[2-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-3-oxidanylidene-3-(prop-2-ynylamino)propyl]amino]-3-oxidanylidene-propyl]amino]-2-oxidanylidene-ethyl]-2,3-bis(oxidanyl)benzamide (3 entities in total)
• Functional Keywords: pfee, pa2689, hydrolase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 2
• Total formula weight: 62792.41

Authors

Moynie, L.,Naismith, J.H. (deposition date: 2018-05-09, release date: 2018-06-20, Last modification date: 2018-10-03)

• Primary citation: Perraud, Q.,Moynie, L.,Gasser, V.,Munier, M.,Godet, J.,Hoegy, F.,Mely, Y.,Mislin, G.L.A.,Naismith, J.H.,Schalk, I.J.; A Key Role for the Periplasmic PfeE Esterase in Iron Acquisition via the Siderophore Enterobactin in Pseudomonas aeruginosa.; ACS Chem. Biol., 13:2603-2614, 2018; PubMed: 30086222; DOI: 10.1021/acschembio.8b00543

Experimental method

X-RAY DIFFRACTION (3.11 Å)