6GH7

WILDTYPE CORE-STREPTAVIDIN WITH a conjugated BIOTINYLATED PYRROLIDINE

6GH7 の概要

• エントリーDOI: 10.2210/pdb6gh7/pdb
• 分子名称: Streptavidin, 5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]-~{N}-[(3~{R})-pyrrolidin-3-yl]pentanamide (3 entities in total)
• 機能のキーワード: biotin-binding protein, organocatalysis, supramolecular chemistry, secondary amine, artificial enzyme
• 由来する生物種: Streptomyces avidinii
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 54899.85

構造登録者

Nodling, A.R.,Tsai, Y.H.,Luk, L.Y.P.,Rizkallah, P.,Jin, Y. (登録日: 2018-05-04, 公開日: 2018-10-10, 最終更新日: 2024-01-17)

• 主引用文献: Nodling, A.R.,Swiderek, K.,Castillo, R.,Hall, J.W.,Angelastro, A.,Morrill, L.C.,Jin, Y.,Tsai, Y.H.,Moliner, V.,Luk, L.Y.P.; Reactivity and Selectivity of Iminium Organocatalysis Improved by a Protein Host.; Angew.Chem.Int.Ed.Engl., 57:12478-12482, 2018; PubMed: 30027571; DOI: 10.1002/anie.201806850

実験手法

X-RAY DIFFRACTION (1.08 Å)