6GH6

Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme intermediate partially loaded complex

6GH6 の概要

• エントリーDOI: 10.2210/pdb6gh6/pdb
• EMDBエントリー: 0002 4397
• 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (7 entities in total)
• 機能のキーワード: transcription initiation, dna loading, transcription bubble, sigma factor, transcription
• 由来する生物種: Escherichia coli (strain K12); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 483181.50

構造登録者

Glyde, R.,Ye, F.Z.,Zhang, X.D. (登録日: 2018-05-04, 公開日: 2018-07-04, 最終更新日: 2024-05-15)

• 主引用文献: Glyde, R.,Ye, F.,Jovanovic, M.,Kotta-Loizou, I.,Buck, M.,Zhang, X.; Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation.; Mol. Cell, 70:1111-1120.e3, 2018; PubMed: 29932903; DOI: 10.1016/j.molcel.2018.05.021

実験手法

ELECTRON MICROSCOPY (4.1 Å)