6GF8

Molecular basis of egg coat filament cross-linking: structure of the glycosylated ZP1 ZP-N1 domain homodimer

Summary for 6GF8

• Entry DOI: 10.2210/pdb6gf8/pdb
• Related: 6GF6 6GF7
• Descriptor: Zona pellucida sperm-binding protein 1,Zona pellucida sperm-binding protein 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: zona pellucida, zp1, zp-n domain, zp module, zp domain, egg coat filament cross-linking, egg coat penetration by sperm, cell adhesion
• Biological source: Gallus gallus (Chicken); More
• Total number of polymer chains: 2
• Total formula weight: 32438.61

Authors

Nishimura, K.,Jovine, L. (deposition date: 2018-04-29, release date: 2019-06-19, Last modification date: 2024-01-17)

• Primary citation: Nishimura, K.,Dioguardi, E.,Nishio, S.,Villa, A.,Han, L.,Matsuda, T.,Jovine, L.; Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility.; Nat Commun, 10:3086-3086, 2019; PubMed: 31300655; DOI: 10.1038/s41467-019-10931-5

Experimental method

X-RAY DIFFRACTION (3.1 Å)