6GCF
DNA binding domain of restriction endonuclease McrBC in complex with N4-methylcytosine DNA
Summary for 6GCF
Entry DOI | 10.2210/pdb6gcf/pdb |
Related | 6GCD 6GCE |
Descriptor | 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*CP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(C34)P*CP*GP*GP*TP*CP*TP*C)-3'), ... (4 entities in total) |
Functional Keywords | n4-methylcytosine, restriction endonuclease, mcrbc, base flipping, dna binding protein |
Biological source | Escherichia coli More |
Total number of polymer chains | 4 |
Total formula weight | 46660.65 |
Authors | Sasnauskas, G. (deposition date: 2018-04-17, release date: 2018-09-19, Last modification date: 2024-01-17) |
Primary citation | Zagorskaite, E.,Manakova, E.,Sasnauskas, G. Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC. FEBS Lett., 592:3335-3345, 2018 Cited by PubMed: 30194838DOI: 10.1002/1873-3468.13244 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
Download full validation report