6GCD

DNA binding domain of restriction endonuclease McrBC in complex with 5-hydroxymethylcytosine DNA

6GCD の概要

• エントリーDOI: 10.2210/pdb6gcd/pdb
• 分子名称: 5-methylcytosine-specific restriction enzyme B, DNA (5'-D(*GP*AP*GP*AP*(5HC)P*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*(5HC)P*CP*GP*GP*TP*CP*TP*C)-3'), ... (4 entities in total)
• 機能のキーワード: 5-hydroxymethylcytosine, restriction endonuclease, mcrbc, base flipping, dna binding protein
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 46858.91

構造登録者

Sasnauskas, G.,Manakova, E. (登録日: 2018-04-17, 公開日: 2018-09-19, 最終更新日: 2024-01-17)

• 主引用文献: Zagorskaite, E.,Manakova, E.,Sasnauskas, G.; Recognition of modified cytosine variants by the DNA-binding domain of methyl-directed endonuclease McrBC.; FEBS Lett., 592:3335-3345, 2018; PubMed: 30194838; DOI: 10.1002/1873-3468.13244

実験手法

X-RAY DIFFRACTION (1.8 Å)