6G9B

Crystal structure of Ebolavirus glycoprotein in complex with imipramine

6G9B の概要

• エントリーDOI: 10.2210/pdb6g9b/pdb
• 関連するPDBエントリー: 6G95
• 分子名称: Envelope glycoprotein,Envelope glycoprotein, Envelope glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: ebolavirus glycoprotein, imipramine, protein drug complex, viral protein
• 由来する生物種: Zaire ebolavirus (strain Mayinga-76) (ZEBOV); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 57882.05

構造登録者

Zhao, Y.,Ren, J.,Fry, E.E.,Xiao, J.,Townsend, A.R.,Stuart, D.I. (登録日: 2018-04-10, 公開日: 2018-05-23, 最終更新日: 2020-07-29)

• 主引用文献: Zhao, Y.,Ren, J.,Fry, E.E.,Xiao, J.,Townsend, A.R.,Stuart, D.I.; Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.; J. Med. Chem., 61:4938-4945, 2018; PubMed: 29741894; DOI: 10.1021/acs.jmedchem.8b00350

実験手法

X-RAY DIFFRACTION (2.26 Å)