6G8P

14-3-3sigma in complex with a P129beta3P and L132beta3L mutated YAP pS127 phosphopeptide

6G8P の概要

• エントリーDOI: 10.2210/pdb6g8p/pdb
• 関連するPDBエントリー: 6g6x 6g8i 6g8j 6g8k 6g8l
• 分子名称: 14-3-3 protein sigma, Transcriptional coactivator YAP1, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: beta amino acid, hippo pathway, yap/taz, oncoprotein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 27847.74

構造登録者

Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. (登録日: 2018-04-09, 公開日: 2019-04-17, 最終更新日: 2024-01-17)

• 主引用文献: Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G.; A study on the effect of synthetic alpha-to-beta3-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins.; Chem.Commun.(Camb.), 55:14809-14812, 2019; PubMed: 31763628; DOI: 10.1039/c9cc07982c

実験手法

X-RAY DIFFRACTION (1.9 Å)