6G8L

14-3-3sigma in complex with a L132beta3L mutated YAP pS127 phosphopeptide

Summary for 6G8L

Related6g8i 6g6x 6g8j 6g8k
Descriptor14-3-3 protein sigma, ACE-ARG-ALA-HIS-SEP-SER-PRO-ALA-SER-BLE-GLN, CHLORIDE ION, ... (6 entities in total)
Functional Keywordsbeta amino acid, hippo pathway, yap/taz, oncoprotein
Biological sourceHomo sapiens (Human)
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Total number of polymer chains2
Total molecular weight27800.85
Authors
Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. (deposition date: 2018-04-09, release date: 2019-04-17)
Primary citation
Thijssen, V.,Andrei, S.A.,Brunsveld, L.,Ottmann, C.,Milroy, L.G.
Effect of single, synthetic alpha-to-beta3-amino acid point mutations on phosphopeptide-protein binding
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.37 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.157400 3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6g8l
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Molmil generated image of 6g8l
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Molmil generated image of 6g8l
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More Biological unit images

Molmil generated image of 6g8l
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Molmil generated image of 6g8l
rotated about x axis by 90°
Molmil generated image of 6g8l
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6g8l.pdb1.gz [280.97 KB])