6G8I
14-3-3sigma in complex with a R124beta3R mutated YAP pS127 phosphopeptide
Summary for 6G8I
Entry DOI | 10.2210/pdb6g8i/pdb |
Descriptor | 14-3-3 protein sigma, ALA-HIS-SEP-SER-PRO-ALA-SER-LEU-GLN, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | beta amino acid hippo pathway yap/taz, oncoprotein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 27822.83 |
Authors | Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. (deposition date: 2018-04-09, release date: 2019-04-17, Last modification date: 2024-02-07) |
Primary citation | Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. A study on the effect of synthetic alpha-to-beta3-amino acid mutations on the binding of phosphopeptides to 14-3-3 proteins. Chem.Commun.(Camb.), 55:14809-14812, 2019 Cited by PubMed: 31763628DOI: 10.1039/c9cc07982c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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