6G8I

14-3-3sigma in complex with a R124beta3R mutated YAP pS127 phosphopeptide

Summary for 6G8I

Descriptor14-3-3 protein sigma, ALA-HIS-SEP-SER-PRO-ALA-SER-LEU-GLN, CHLORIDE ION, ... (6 entities in total)
Functional Keywordsbeta amino acid hippo pathway yap/taz, oncoprotein
Biological sourceHomo sapiens (Human)
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Total number of polymer chains2
Total molecular weight27862.81
Authors
Andrei, S.A.,Thijssen, V.,Brunsveld, L.,Ottmann, C.,Milroy, L.G. (deposition date: 2018-04-09, release date: 2019-04-17)
Primary citation
Thijssen, V.,Andrei, S.A.,Brunsveld, L.,Ottmann, C.,Milroy, L.G.
Effect of single, synthetic alpha-to-beta3-amino acid point mutations on phosphopeptide-protein binding
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.173400 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6g8i
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Molmil generated image of 6g8i
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Molmil generated image of 6g8i
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More Biological unit images

Molmil generated image of 6g8i
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Molmil generated image of 6g8i
rotated about x axis by 90°
Molmil generated image of 6g8i
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (6g8i.pdb1.gz [180.75 KB])