6G2V

Crystal structure of the p97 D2 domain in a helical split-washer conformation

Summary for 6G2V

• Entry DOI: 10.2210/pdb6g2v/pdb
• Descriptor: Transitional endoplasmic reticulum ATPase, (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: atpase, p97, protein degradation, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 31939.62

Authors

Stach, L.,Morgan, R.M.L.,Freemont, P.S. (deposition date: 2018-03-23, release date: 2019-04-10, Last modification date: 2024-01-17)

• Primary citation: Stach, L.,Morgan, R.M.,Makhlouf, L.,Douangamath, A.,von Delft, F.,Zhang, X.,Freemont, P.S.; Crystal structure of the catalytic D2 domain of the AAA+ ATPase p97 reveals a putative helical split-washer-type mechanism for substrate unfolding.; Febs Lett., 594:933-943, 2020; PubMed: 31701538; DOI: 10.1002/1873-3468.13667

Experimental method

X-RAY DIFFRACTION (1.903 Å)