6G2V

Crystal structure of the p97 D2 domain in a helical split-washer conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Transitional endoplasmic reticulum ATPase	polymer	275	30961.6	1	UniProt (P55072) Pfam (PF00004) Pfam (PF17862) In PDB	Homo sapiens (Human)	TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2	A	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	4	Chemie (MPD)
3	A	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS)
4	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
5		water	water		18.0	130	Chemie (HOH)

Sequence modifications

A: 462 - 764 (UniProt: P55072)

PDB	External Database	Details
Gly 459	-	expression tag
Pro 460	-	expression tag
Gly 461	-	expression tag
-	Met 550	deletion
-	Trp 551	deletion
-	Phe 552	deletion
-	Gly 553	deletion
-	Glu 554	deletion
-	Ala 585	deletion
-	Arg 586	deletion
-	Gly 587	deletion
-	Gly 588	deletion
-	Asn 589	deletion
-	Ile 590	deletion
-	Gly 591	deletion
-	Asp 592	deletion
-	Gly 593	deletion
-	Gly 594	deletion
-	Gly 595	deletion
-	Arg 713	deletion
-	Gln 714	deletion
-	Thr 715	deletion
-	Asn 716	deletion
-	Pro 717	deletion
-	Ser 718	deletion
-	Ala 719	deletion
-	Met 720	deletion
-	Glu 721	deletion
-	Val 722	deletion
-	Glu 723	deletion
-	Glu 724	deletion
-	Asp 725	deletion
-	Asp 726	deletion
-	Pro 727	deletion

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	30961.6
Non-Polymers*	Number of molecules	6
	Total formula weight	978.0
All*	Total formula weight	31939.6

*Water molecules are not included.