6FZX
LasB, hydroxymate Inhibitor Complex
Summary for 6FZX
| Entry DOI | 10.2210/pdb6fzx/pdb |
| Descriptor | Keratinase KP2, ~{N}-(3,4-dichlorophenyl)-~{N}'-oxidanyl-propanediamide, ZINC ION, ... (7 entities in total) |
| Functional Keywords | lasb, hydroxymate inhibitor complex, hydrolase |
| Biological source | Pseudomonas aeruginosa |
| Total number of polymer chains | 1 |
| Total formula weight | 33732.25 |
| Authors | Koehnke, J.,Sikandar, A. (deposition date: 2018-03-15, release date: 2018-09-05, Last modification date: 2024-01-17) |
| Primary citation | Kany, A.M.,Sikandar, A.,Yahiaoui, S.,Haupenthal, J.,Walter, I.,Empting, M.,Kohnke, J.,Hartmann, R.W. Tackling Pseudomonas aeruginosa Virulence by a Hydroxamic Acid-Based LasB Inhibitor. ACS Chem. Biol., 13:2449-2455, 2018 Cited by PubMed: 30088919DOI: 10.1021/acschembio.8b00257 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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