6FZS

Crystal structure of Smad5-MH1 bound to the GGCGC site.

Summary for 6FZS

• Entry DOI: 10.2210/pdb6fzs/pdb
• Descriptor: Mothers against decapentaplegic homolog 5, DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP*GP*CP*A)-3'), ZINC ION, ... (4 entities in total)
• Functional Keywords: smads, transcription factor, dna complex, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 40148.36

Authors

Kaczmarska, Z.,Marquez, J.A.,Macias, M.J. (deposition date: 2018-03-15, release date: 2019-10-02, Last modification date: 2024-01-17)

• Primary citation: Ruiz, L.,Kaczmarska, Z.,Gomes, T.,Aragon, E.,Torner, C.,Freier, R.,Baginski, B.,Martin-Malpartida, P.,Marquez, J.A.,Cordeiro, T.N.,Pluta, R.,Macias, M.J.; Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes; Computational and Structural Biotechnology Journal, 19:-, 2021; DOI: 10.1016/j.csbj.2020.12.044

Experimental method

X-RAY DIFFRACTION (2.31 Å)