6FZJ

PPAR gamma mutant complex

6FZJ の概要

• エントリーDOI: 10.2210/pdb6fzj/pdb
• 分子名称: Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, (2~{S})-3-[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]-2-[[2-(phenylcarbonyl)phenyl]amino]propanoic acid, ... (6 entities in total)
• 機能のキーワード: nuclear receptor, transcription
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 67297.43

構造登録者

Rochel, N. (登録日: 2018-03-14, 公開日: 2019-02-13, 最終更新日: 2024-01-17)

• 主引用文献: Rochel, N.,Krucker, C.,Coutos-Thevenot, L.,Osz, J.,Zhang, R.,Guyon, E.,Zita, W.,Vanthong, S.,Hernandez, O.A.,Bourguet, M.,Badawy, K.A.,Dufour, F.,Peluso-Iltis, C.,Heckler-Beji, S.,Dejaegere, A.,Kamoun, A.,de Reynies, A.,Neuzillet, Y.,Rebouissou, S.,Beraud, C.,Lang, H.,Massfelder, T.,Allory, Y.,Cianferani, S.,Stote, R.H.,Radvanyi, F.,Bernard-Pierrot, I.; Recurrent activating mutations of PPAR gamma associated with luminal bladder tumors.; Nat Commun, 10:253-253, 2019; PubMed: 30651555; DOI: 10.1038/s41467-018-08157-y

実験手法

X-RAY DIFFRACTION (2.011 Å)