6FYV
X-RAY STRUCTURE OF CLK4-KD(146-480)/CX-4945 AT 2.46A
Summary for 6FYV
Entry DOI | 10.2210/pdb6fyv/pdb |
Related | 6FYI 6FYK 6FYL 6FYO 6FYP 6FYR |
Descriptor | Dual specificity protein kinase CLK4, 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | splicing, kinase, phosphotransferase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 40329.45 |
Authors | Kallen, J. (deposition date: 2018-03-12, release date: 2018-07-18, Last modification date: 2024-01-17) |
Primary citation | Kallen, J.,Bergsdorf, C.,Arnaud, B.,Bernhard, M.,Brichet, M.,Cobos-Correa, A.,Elhajouji, A.,Freuler, F.,Galimberti, I.,Guibourdenche, C.,Haenni, S.,Holzinger, S.,Hunziker, J.,Izaac, A.,Kaufmann, M.,Leder, L.,Martus, H.J.,von Matt, P.,Polyakov, V.,Roethlisberger, P.,Roma, G.,Stiefl, N.,Uteng, M.,Lerchner, A. X-ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan-McDermid Syndrome. ChemMedChem, 13:1997-2007, 2018 Cited by PubMed: 29985556DOI: 10.1002/cmdc.201800344 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.46 Å) |
Structure validation
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