6FY3
Crystal structure of a V2-directed, RV144 vaccine-like antibody from HIV-1 infection, CAP228-3D, bound to a heterologous V2 peptide
Summary for 6FY3
| Entry DOI | 10.2210/pdb6fy3/pdb |
| Descriptor | CAP228-3D Heavy Chain, CAP228-3D Light Chain, CAP45 V2 peptide, ... (4 entities in total) |
| Functional Keywords | fab, hiv-1 envelope v1v2, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 6 |
| Total formula weight | 103101.05 |
| Authors | Wibmer, C.K.,Moore, P.L.,Morris, L. (deposition date: 2018-03-10, release date: 2018-09-05, Last modification date: 2024-01-17) |
| Primary citation | Wibmer, C.K.,Richardson, S.I.,Yolitz, J.,Cicala, C.,Arthos, J.,Moore, P.L.,Morris, L. Common helical V1V2 conformations of HIV-1 Envelope expose the alpha 4 beta 7 binding site on intact virions. Nat Commun, 9:4489-4489, 2018 Cited by PubMed: 30367034DOI: 10.1038/s41467-018-06794-x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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