6FX3

crystal structure of Pholiota squarrosa lectin in complex with a dodecasaccharide

Summary for 6FX3

• Entry DOI: 10.2210/pdb6fx3/pdb
• Descriptor: lectin, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]1-azido-beta-N-acetyl-D-glucosamine, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]1-azido-beta-N-acetyl-D-glucosamine, ... (4 entities in total)
• Functional Keywords: lectin, dodecasaccharide, sugar binding protein
• Biological source: Pholiota squarrosa
• Total number of polymer chains: 2
• Total formula weight: 12940.72

Authors

Cabanettes, A.,Varrot, A. (deposition date: 2018-03-08, release date: 2018-07-11, Last modification date: 2024-05-01)

• Primary citation: Cabanettes, A.,Perkams, L.,Spies, C.,Unverzagt, C.,Varrot, A.; Recognition of Complex Core-Fucosylated N-Glycans by a Mini Lectin.; Angew. Chem. Int. Ed. Engl., 57:10178-10181, 2018; PubMed: 29956878; DOI: 10.1002/anie.201805165

Experimental method

X-RAY DIFFRACTION (1.7 Å)