6FVS
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with Barium ions (Ba2+)
Summary for 6FVS
| Entry DOI | 10.2210/pdb6fvs/pdb |
| Descriptor | Cys-loop ligand-gated ion channel, nonyl beta-D-glucopyranoside, BARIUM ION, ... (5 entities in total) |
| Functional Keywords | pentameric ligand-gated ion channel., membrane protein |
| Biological source | endosymbiont of Tevnia jerichonana (vent Tica) |
| Total number of polymer chains | 5 |
| Total formula weight | 188426.14 |
| Authors | Hu, H.,Delarue, M. (deposition date: 2018-03-05, release date: 2018-05-16, Last modification date: 2024-05-08) |
| Primary citation | Hu, H.,Nemecz, A.,Van Renterghem, C.,Fourati, Z.,Sauguet, L.,Corringer, P.J.,Delarue, M. Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation. Proc. Natl. Acad. Sci. U.S.A., 115:E3959-E3968, 2018 Cited by PubMed: 29632192DOI: 10.1073/pnas.1717700115 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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