6FTM

Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-048

Summary for 6FTM

• Entry DOI: 10.2210/pdb6ftm/pdb
• Descriptor: Phosphodiesterase, MAGNESIUM ION, ZINC ION, ... (8 entities in total)
• Functional Keywords: parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 84265.26

Authors

Singh, A.K.,Brown, D.G. (deposition date: 2018-02-22, release date: 2019-03-20, Last modification date: 2024-01-17)

• Primary citation: de Heuvel, E.,Singh, A.K.,Brown, D.G.; Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-048; To be published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)