6FT0

Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-425

Summary for 6FT0

• Entry DOI: 10.2210/pdb6ft0/pdb
• Related: 6FRD
• Descriptor: cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: phosphodiesterase, hydrolase, camp hydrolysis, alternative splicing
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 174147.52

Authors

Singh, A.K.,Brown, D.G. (deposition date: 2018-02-20, release date: 2019-03-20, Last modification date: 2024-01-17)

• Primary citation: Singh, A.K.,Brown, D.G.; hPDE4D2 structure with inhibitor NPD-425; To be published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)