6FSO
Crystal Structure of TGT in complex with methyl({[5-(pyridin-3-yloxy)furan-2-yl]methyl})amine
Summary for 6FSO
Entry DOI | 10.2210/pdb6fso/pdb |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, DI(HYDROXYETHYL)ETHER, ... (9 entities in total) |
Functional Keywords | tgt, trna, guanine exchange enzyme, protein interface, transferase |
Biological source | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) |
Total number of polymer chains | 1 |
Total formula weight | 42833.05 |
Authors | Hassaan, E.,Heine, A.,Klebe, G. (deposition date: 2018-02-20, release date: 2019-03-20, Last modification date: 2024-01-17) |
Primary citation | Hassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G. Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15:324-337, 2020 Cited by PubMed: 31808981DOI: 10.1002/cmdc.201900604 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.449 Å) |
Structure validation
Download full validation report