6FSN

Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-glucose (conformation 1)

6FSN の概要

• エントリーDOI: 10.2210/pdb6fsn/pdb
• 関連するPDBエントリー: 5MU1 5MZO 5N2J 5NV4
• 分子名称: UDP-glucose-glycoprotein glucosyltransferase-like protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (7 entities in total)
• 機能のキーワード: glycoprotein, misfolding, transferase, endoplasmic reticulum. udp-glucose, gt24
• 由来する生物種: Chaetomium thermophilum
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36527.20

構造登録者

Roversi, P.,Le Cornu, J.D.,Hill, J.,Alonzi, D.S.,Zitzmann, N. (登録日: 2018-02-19, 公開日: 2019-03-20, 最終更新日: 2024-10-16)

• 主引用文献: Caputo, A.T.,Ibba, R.,Le Cornu, J.D.,Darlot, B.,Hensen, M.,Lipp, C.B.,Marciano, G.,Vasiljevic, S.,Zitzmann, N.,Roversi, P.; Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint.; Front Mol Biosci, 2022; DOI: 10.3389/fmolb.2022.960248

実験手法

X-RAY DIFFRACTION (1.19 Å)