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6FS9

Influenza B/Memphis/13/03 endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)

Summary for 6FS9
Entry DOI10.2210/pdb6fs9/pdb
DescriptorPolymerase acidic protein, MANGANESE (II) ION, Baloxavir acid, ... (5 entities in total)
Functional Keywordsinfluenza polymerase, endonuclease, inhibitor, viral protein
Biological sourceInfluenza B virus (B/Memphis/13/2003)
Total number of polymer chains1
Total formula weight24170.87
Authors
Cusack, S.,Speranzini, V. (deposition date: 2018-02-19, release date: 2018-07-11, Last modification date: 2024-01-17)
Primary citationOmoto, S.,Speranzini, V.,Hashimoto, T.,Noshi, T.,Yamaguchi, H.,Kawai, M.,Kawaguchi, K.,Uehara, T.,Shishido, T.,Naito, A.,Cusack, S.
Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8:9633-9633, 2018
Cited by
PubMed: 29941893
DOI: 10.1038/s41598-018-27890-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.28 Å)
Structure validation

218500

건을2024-04-17부터공개중

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