6FRX

PKA variant as Aurora B mimic in complex with a dianilinopyrimidine inhibitor

Summary for 6FRX

• Entry DOI: 10.2210/pdb6frx/pdb
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, ~{N}-[3-[(5-chloranyl-2-phenylazanyl-pyrimidin-4-yl)amino]phenyl]prop-2-enamide, ... (4 entities in total)
• Functional Keywords: protein kinase, surrogate model, catalytic domain, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 43448.69

Authors

Engh, R.A.,Kazi, A.A. (deposition date: 2018-02-16, release date: 2019-03-13)

• Primary citation: Engh, R.A.,Kazi, A.A.; PKA variant as Aurora B mimic in complex with a dianilinopyrimidine inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.88 Å)