6FO7

Vitamin D nuclear receptor complex 3

Summary for 6FO7

• Entry DOI: 10.2210/pdb6fo7/pdb
• Descriptor: Vitamin D3 receptor A, Nuclear receptor coactivator 1, (1~{R},3~{S},5~{Z})-4-methylidene-5-[(~{E})-3-[3-(6-methyl-6-oxidanyl-heptyl)phenyl]hept-2-enylidene]cyclohexane-1,3-diol, ... (4 entities in total)
• Functional Keywords: gene regulation
• Biological source: Danio rerio (Zebrafish); More
• Total number of polymer chains: 2
• Total formula weight: 36119.25

Authors

Rochel, N. (deposition date: 2018-02-06, release date: 2018-05-16, Last modification date: 2024-01-17)

• Primary citation: Gogoi, P.,Seoane, S.,Sigueiro, R.,Guiberteau, T.,Maestro, M.A.,Perez-Fernandez, R.,Rochel, N.,Mourino, A.; Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists.; J. Med. Chem., 61:4928-4937, 2018; PubMed: 29733645; DOI: 10.1021/acs.jmedchem.8b00337

Experimental method

X-RAY DIFFRACTION (2.59 Å)