6FNU

Structure of S. cerevisiae Methylenetetrahydrofolate reductase 1, catalytic domain

6FNU の概要

• エントリーDOI: 10.2210/pdb6fnu/pdb
• 分子名称: Methylenetetrahydrofolate reductase 1, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: reductase, one carbon metabolism, tim barrel, folate metabolism, structural genomics, structural genomics consortium, sgc, oxidoreductase
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 35580.30

構造登録者

Kopec, J.,Rembeza, E.,Bezerra, G.A.,Newman, J.,Bountra, C.,Froese, D.S.,Baumgartner, M.,Yue, W.W.,Structural Genomics Consortium (SGC) (登録日: 2018-02-05, 公開日: 2018-03-07, 最終更新日: 2024-05-08)

• 主引用文献: Froese, D.S.,Kopec, J.,Rembeza, E.,Bezerra, G.A.,Oberholzer, A.E.,Suormala, T.,Lutz, S.,Chalk, R.,Borkowska, O.,Baumgartner, M.R.,Yue, W.W.; Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition.; Nat Commun, 9:2261-2261, 2018; PubMed: 29891918; DOI: 10.1038/s41467-018-04735-2

実験手法

X-RAY DIFFRACTION (1.56 Å)