6FLC

2C8 Fab bound to EDIII of DenV 2

Summary for 6FLC

• Entry DOI: 10.2210/pdb6flc/pdb
• Descriptor: Light chain of 2C8 Fab, Heavy chain of 2C8 Fab, Domain III of Dengue virus 2, ... (5 entities in total)
• Functional Keywords: dengue virus, antibody, macromolecular complex, viral protein
• Biological source: Mus musculus; More
• Total number of polymer chains: 6
• Total formula weight: 119698.24

Authors

Flanagan, A.,Renner, M.,Grimes, J.M. (deposition date: 2018-01-25, release date: 2018-10-24, Last modification date: 2018-10-31)

• Primary citation: Renner, M.,Flanagan, A.,Dejnirattisai, W.,Puttikhunt, C.,Kasinrerk, W.,Supasa, P.,Wongwiwat, W.,Chawansuntati, K.,Duangchinda, T.,Cowper, A.,Midgley, C.M.,Malasit, P.,Huiskonen, J.T.,Mongkolsapaya, J.,Screaton, G.R.,Grimes, J.M.; Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus.; Nat. Immunol., 19:1248-1256, 2018; PubMed: 30323338; DOI: 10.1038/s41590-018-0227-7

Experimental method

X-RAY DIFFRACTION (2 Å)