6FKL
Tubulin-TUB015 complex
Summary for 6FKL
Entry DOI | 10.2210/pdb6fkl/pdb |
Descriptor | Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-{1-[(2-Methoxyphenyl)amino]ethylidene}-5-phenyl-1,3-cyclohexanedione, ... (13 entities in total) |
Functional Keywords | cell cycle, tubulin fold, cytoskeleton, microtubule |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasm, cytoskeleton: P81947 Q6B856 Golgi apparatus : P63043 |
Total number of polymer chains | 6 |
Total formula weight | 265441.42 |
Authors | Prota, A.E.,Steinmetz, M.O.,Priego, E.-M. (deposition date: 2018-01-24, release date: 2018-03-21, Last modification date: 2024-01-17) |
Primary citation | Bueno, O.,Estevez Gallego, J.,Martins, S.,Prota, A.E.,Gago, F.,Gomez-SanJuan, A.,Camarasa, M.J.,Barasoain, I.,Steinmetz, M.O.,Diaz, J.F.,Perez-Perez, M.J.,Liekens, S.,Priego, E.M. High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design. Sci Rep, 8:4242-4242, 2018 Cited by PubMed: 29523799DOI: 10.1038/s41598-018-22382-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.098 Å) |
Structure validation
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