6FJF
Tubulin-FcMaytansine complex
Summary for 6FJF
Entry DOI | 10.2210/pdb6fjf/pdb |
Related | 6FII |
Descriptor | Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... (14 entities in total) |
Functional Keywords | cell cycle, tubulin fold, cytoskeleton, microtubule |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 6 |
Total formula weight | 266095.62 |
Authors | Menchon, G.,Prota, A.E.,Lucena Angell, D.,Bucher, P.,Mueller, R.,Paterson, I.,Diaz, J.F.,Altmann, K.-H.,Steinmetz, M.O. (deposition date: 2018-01-22, release date: 2018-05-30, Last modification date: 2024-01-17) |
Primary citation | Menchon, G.,Prota, A.E.,Lucena-Agell, D.,Bucher, P.,Jansen, R.,Irschik, H.,Muller, R.,Paterson, I.,Diaz, J.F.,Altmann, K.H.,Steinmetz, M.O. A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin. Nat Commun, 9:2106-2106, 2018 Cited by PubMed: 29844393DOI: 10.1038/s41467-018-04535-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.402 Å) |
Structure validation
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