6FI1

Crystal structure of human BAZ2B PHD zinc finger in complex with Fr23

Summary for 6FI1

• Entry DOI: 10.2210/pdb6fi1/pdb
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2B, ZINC ION, ~{N}-(4-aminophenyl)-2-azanyl-ethanamide (3 entities in total)
• Functional Keywords: transcription, phd, zinc finger, baz2b, baz2a, bromodomain, fragment, epigenetic
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : Q9UIF8
• Total number of polymer chains: 2
• Total formula weight: 13514.24

Authors

Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A. (deposition date: 2018-01-16, release date: 2018-03-21, Last modification date: 2024-01-17)

• Primary citation: Amato, A.,Lucas, X.,Bortoluzzi, A.,Wright, D.,Ciulli, A.; Targeting Ligandable Pockets on Plant Homeodomain (PHD) Zinc Finger Domains by a Fragment-Based Approach.; ACS Chem. Biol., 13:915-921, 2018; PubMed: 29529862; DOI: 10.1021/acschembio.7b01093

Experimental method

X-RAY DIFFRACTION (2.7 Å)