6FFD

Human BRD4 C-terminal bromodomain with 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone

Summary for 6FFD

• Entry DOI: 10.2210/pdb6ffd/pdb
• Descriptor: Bromodomain-containing protein 4, 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone (3 entities in total)
• Functional Keywords: inhibitor, histone, epigenetic reader, bromodomain, brd4, bromodomain containing protein 4, antagonist, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 13917.08

Authors

Chung, C. (deposition date: 2018-01-06, release date: 2019-01-30)

• Primary citation: Chung, C.; Design and Synthesis of Tetrahydroquinoxalines as Domain Selective BET Inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.83 Å)