6FF3

Crystal structure of Drosophila neural ectodermal development factor Imp-L1 with Human IGF-I

6FF3 の概要

• エントリーDOI: 10.2210/pdb6ff3/pdb
• 関連するPDBエントリー: 1GZR 4CBP
• 分子名称: Neural/ectodermal development factor IMP-L2, Insulin-like growth factor I (3 entities in total)
• 機能のキーワード: igf-i, insulin binding protein, drosophila, imaginal morphogenesis, peptide binding protein
• 由来する生物種: Drosophila melanogaster (Fruit fly); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34954.41

構造登録者

Brzozowski, A.M.,Kulahin, N.,Kristensen, O.,Schluckebier, G.,Meyts, P.D.,Viola, C.M. (登録日: 2018-01-03, 公開日: 2018-09-26, 最終更新日: 2024-01-17)

• 主引用文献: Roed, N.K.,Viola, C.M.,Kristensen, O.,Schluckebier, G.,Norrman, M.,Sajid, W.,Wade, J.D.,Andersen, A.S.,Kristensen, C.,Ganderton, T.R.,Turkenburg, J.P.,De Meyts, P.,Brzozowski, A.M.; Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability of insulin-like hormones.; Nat Commun, 9:3860-3860, 2018; PubMed: 30242155; DOI: 10.1038/s41467-018-06192-3

実験手法

X-RAY DIFFRACTION (2.57 Å)