6FDY
Unc-51-Like Kinase 3 (ULK3) In Complex With Bosutinib
Summary for 6FDY
Entry DOI | 10.2210/pdb6fdy/pdb |
Descriptor | Serine/threonine-protein kinase ULK3, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile (3 entities in total) |
Functional Keywords | kinase inhibitor dfg-in, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 33000.87 |
Authors | Mathea, S.,Salah, E.,Moroglu, M.,Scorah, A.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Knapp, S. (deposition date: 2017-12-27, release date: 2018-08-01, Last modification date: 2024-01-17) |
Primary citation | Mathea, S.,Salah, E.,Moroglu, M.,Scorah, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Knapp, S. Unc-51-Like Kinase 3 (ULK3) In Complex With Bosutinib To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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