6FDX

Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-1086

Summary for 6FDX

• Entry DOI: 10.2210/pdb6fdx/pdb
• Related: 6FDI 6FDS 6FDW
• Descriptor: Phosphodiesterase, ZINC ION, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: parasitic phosphodiesterase, hydrolase, african trypanosomiasis, sleeping sickness
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 82963.74

Authors

Singh, A.K.,Brown, D.G. (deposition date: 2017-12-27, release date: 2019-04-10, Last modification date: 2024-05-08)

• Primary citation: Salado, I.G.,Moreno, C.,Sakaine, G.,Singh, A.K.,Blaazer, A.R.,Siderius, M.,Matheeussen, A.,Gul, S.,Maes, L.,Leurs, R.,Brown, D.G.,Augustyns, K.; TbrPDEB1 structure with inhibitor NPD-1086; To be published,

Experimental method