6FDU

Structure of Chlamydia trachomatis effector protein Cdu1 bound to Compound 3

6FDU の概要

• エントリーDOI: 10.2210/pdb6fdu/pdb
• 関連するPDBエントリー: 6FDK 6FDQ
• 分子名称: Deubiquitinase and deneddylase Dub1, CHLORIDE ION, (2~{S},3~{S})-2-[[(2~{S})-2-[3,5-bis(chloranyl)phenyl]-2-(dimethylamino)ethanoyl]amino]-~{N}-[[2-(iminomethyl)pyrimidin-4-yl]methyl]-3-methyl-pentanamide, ... (4 entities in total)
• 機能のキーワード: chladub1, ce protease, dub, ubiquitin, covalent inhibitor., hydrolase
• 由来する生物種: Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 61619.02

構造登録者

Ramirez, Y.,Kisker, C.,Altmann, E. (登録日: 2017-12-26, 公開日: 2018-08-15, 最終更新日: 2024-01-17)

• 主引用文献: Ramirez, Y.A.,Adler, T.B.,Altmann, E.,Klemm, T.,Tiesmeyer, C.,Sauer, F.,Kathman, S.G.,Statsyuk, A.V.,Sotriffer, C.,Kisker, C.; Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis.; ChemMedChem, 13:2014-2023, 2018; PubMed: 30028574; DOI: 10.1002/cmdc.201800364

実験手法

X-RAY DIFFRACTION (2.3 Å)