6FDU
Structure of Chlamydia trachomatis effector protein Cdu1 bound to Compound 3
Summary for 6FDU
Entry DOI | 10.2210/pdb6fdu/pdb |
Related | 6FDK 6FDQ |
Descriptor | Deubiquitinase and deneddylase Dub1, CHLORIDE ION, (2~{S},3~{S})-2-[[(2~{S})-2-[3,5-bis(chloranyl)phenyl]-2-(dimethylamino)ethanoyl]amino]-~{N}-[[2-(iminomethyl)pyrimidin-4-yl]methyl]-3-methyl-pentanamide, ... (4 entities in total) |
Functional Keywords | chladub1, ce protease, dub, ubiquitin, covalent inhibitor., hydrolase |
Biological source | Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) |
Total number of polymer chains | 2 |
Total formula weight | 61619.02 |
Authors | Ramirez, Y.,Kisker, C.,Altmann, E. (deposition date: 2017-12-26, release date: 2018-08-15, Last modification date: 2024-01-17) |
Primary citation | Ramirez, Y.A.,Adler, T.B.,Altmann, E.,Klemm, T.,Tiesmeyer, C.,Sauer, F.,Kathman, S.G.,Statsyuk, A.V.,Sotriffer, C.,Kisker, C. Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis. ChemMedChem, 13:2014-2023, 2018 Cited by PubMed: 30028574DOI: 10.1002/cmdc.201800364 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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