6FDU

Structure of Chlamydia trachomatis effector protein Cdu1 bound to Compound 3

Summary for 6FDU

Entry DOI	10.2210/pdb6fdu/pdb
Related	6FDK 6FDQ
Descriptor	Deubiquitinase and deneddylase Dub1, CHLORIDE ION, (2~{S},3~{S})-2-[[(2~{S})-2-[3,5-bis(chloranyl)phenyl]-2-(dimethylamino)ethanoyl]amino]-~{N}-[[2-(iminomethyl)pyrimidin-4-yl]methyl]-3-methyl-pentanamide, ... (4 entities in total)
Functional Keywords	chladub1, ce protease, dub, ubiquitin, covalent inhibitor., hydrolase
Biological source	Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
Total number of polymer chains	2
Total formula weight	61619.02
Authors	Ramirez, Y.,Kisker, C.,Altmann, E. (deposition date: 2017-12-26, release date: 2018-08-15, Last modification date: 2024-01-17)
Primary citation	Ramirez, Y.A.,Adler, T.B.,Altmann, E.,Klemm, T.,Tiesmeyer, C.,Sauer, F.,Kathman, S.G.,Statsyuk, A.V.,Sotriffer, C.,Kisker, C. Structural Basis of Substrate Recognition and Covalent Inhibition of Cdu1 from Chlamydia trachomatis. ChemMedChem, 13:2014-2023, 2018 Cited by PubMed: 30028574 DOI: 10.1002/cmdc.201800364 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation