6FCZ

Model of gC1q-Fc complex based on 7A EM map

Summary for 6FCZ

• Entry DOI: 10.2210/pdb6fcz/pdb
• EMDB information: 4231 4232
• Descriptor: Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, ... (5 entities in total)
• Functional Keywords: complement, antibody, complex, c1, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 93068.24

Authors

Ugurlar, D.,Howes, S.C.,de Kreuk, B.J.K.,de Jong, R.N.,Beurskens, F.J.,Koster, A.J.,Parren, P.W.H.I.,Sharp, T.H.,Gros, P.,Koning, R.I. (deposition date: 2017-12-21, release date: 2018-02-28, Last modification date: 2018-10-24)

• Primary citation: Ugurlar, D.,Howes, S.C.,de Kreuk, B.J.,Koning, R.I.,de Jong, R.N.,Beurskens, F.J.,Schuurman, J.,Koster, A.J.,Sharp, T.H.,Parren, P.W.H.I.,Gros, P.; Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement.; Science, 359:794-797, 2018; PubMed: 29449492; DOI: 10.1126/science.aao4988

Experimental method

ELECTRON MICROSCOPY (10 Å)