6FBZ

Crystal structure of the eIF4E-eIF4G complex from Chaetomium thermophilum in the cap-bound state

6FBZ の概要

• エントリーDOI: 10.2210/pdb6fbz/pdb
• 分子名称: Eukaryotic translation initiation factor 4E-like protein,Eukaryotic translation initiation factor 4E-like protein, Eukaryotic translation initiation factor 4G, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: translation translational control translation initiation gene expression, translation
• 由来する生物種: Chaetomium thermophilum var. thermophilum DSM 1495; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32667.84

構造登録者

Gruener, S.,Valkov, E. (登録日: 2017-12-20, 公開日: 2018-06-27, 最終更新日: 2024-01-17)

• 主引用文献: Gruner, S.,Weber, R.,Peter, D.,Chung, M.Y.,Igreja, C.,Valkov, E.,Izaurralde, E.; Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast.; Nucleic Acids Res., 46:6893-6908, 2018; PubMed: 30053226; DOI: 10.1093/nar/gky542

実験手法

X-RAY DIFFRACTION (1.496 Å)