6FAD

SR protein kinase 1 (SRPK1) in complex with the RGG-box of HSV1 ICP27

Summary for 6FAD

Entry DOI	10.2210/pdb6fad/pdb
Descriptor	SRSF protein kinase 1, mRNA export factor, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	complex, phosphorylation, inhibition, splicing
Biological source	Homo sapiens (Human) More
Total number of polymer chains	8
Total formula weight	287934.00
Authors	Tunnicliffe, R.B.,Levy, C.,Mould, A.P.,Mckenzie, E.A.,Sandri-Goldin, R.M.,Golovanov, A.P. (deposition date: 2017-12-15, release date: 2019-09-25, Last modification date: 2024-01-17)
Primary citation	Tunnicliffe, R.B.,Hu, W.K.,Wu, M.Y.,Levy, C.,Mould, A.P.,McKenzie, E.A.,Sandri-Goldin, R.M.,Golovanov, A.P. Molecular Mechanism of SR Protein Kinase 1 Inhibition by the Herpes Virus Protein ICP27. Mbio, 10:-, 2019 Cited by PubMed: 31641093 DOI: 10.1128/mBio.02551-19 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.801 Å)

Structure validation