6F9U
Crystal structure of human testis Angiotensin-1 converting enzyme in complex with Sampatrilat-Asp.
Summary for 6F9U
| Entry DOI | 10.2210/pdb6f9u/pdb |
| Descriptor | Angiotensin-converting enzyme, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (12 entities in total) |
| Functional Keywords | angiotensin-1 converting enzyme, ace inhibitor, sampatrilat, sampatrilat-asp, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 70985.93 |
| Authors | Cozier, G.E.,Acharya, K.R. (deposition date: 2017-12-15, release date: 2018-03-07, Last modification date: 2024-01-17) |
| Primary citation | Cozier, G.E.,Schwager, S.L.,Sharma, R.K.,Chibale, K.,Sturrock, E.D.,Acharya, K.R. Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE - a molecular basis for domain selectivity. FEBS J., 285:1477-1490, 2018 Cited by PubMed: 29476645DOI: 10.1111/febs.14421 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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