6F8B

LasB bound to thiol based inhibitor

Summary for 6F8B

Entry DOI	10.2210/pdb6f8b/pdb
Descriptor	Elastase, CALCIUM ION, ZINC ION, ... (5 entities in total)
Functional Keywords	lasb, inhibitor, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	33753.25
Authors	Koehnke, J.,Sikandar, A. (deposition date: 2017-12-12, release date: 2018-03-28, Last modification date: 2024-01-17)
Primary citation	Kany, A.M.,Sikandar, A.,Haupenthal, J.,Yahiaoui, S.,Maurer, C.K.,Proschak, E.,Kohnke, J.,Hartmann, R.W. Binding Mode Characterization and Early in Vivo Evaluation of Fragment-Like Thiols as Inhibitors of the Virulence Factor LasB from Pseudomonas aeruginosa. ACS Infect Dis, 4:988-997, 2018 Cited by PubMed: 29485268 DOI: 10.1021/acsinfecdis.8b00010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation